Innovations In Clinical Neuroscience

CNS Summit 2016

A peer-reviewed, evidence-based journal for clinicians in the field of neuroscience

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[ V O L U M E 1 4 , N U M B E R 1 – 2 , J A N U A R Y – F E B R U A R Y 2 0 1 7 , S U P P L E M E N T ] Innovations in CLINICAL NEUROSCIENCE S3 JOURNAL STAFF EDITOR—Amir H. Kalali, MD, Vice President, Global Therapeutic Group Leader CNS, Quintiles Inc.; Professor of Psychiatry, University of California San Diego, California EXECUTIVE EDITOR—Elizabeth A. Klumpp, Matrix Medical Communications, West Chester, Pennsylvania A SSOCIATE EDITOR—Kimberly B. Chesky, Matrix Medical C ommunications, West Chester, Pennsylvania ASSOCIATE EDITOR—Angela M. Saba, Matrix Medical Communications, West Chester, Pennsylvania ASSISTANT EDITOR—Frank Hoskings, III, Matrix Medical Communications, West Chester, Pennsylvania BUSINESS STAFF PRESIDENT/GROUP PUBLISHER—Robert L. Dougherty, Matrix Medical Communications, West Chester, Pennsylvania V ICE PRESIDENT/EDITORIAL DIRECTOR—Elizabeth A. Klumpp, Matrix M edical Communications, West Chester, Pennsylvania VICE PRESIDENT/BUSINESS FINANCE—Christine C. Franey, Matrix Medical Communications, West Chester, Pennsylvania V ICE PRESIDENT/BUSINESS DEVELOPMENT—Joseph J. Morris, Matrix Medical Communications, West Chester, Pennsylvania ASSOC. DIRECTOR/BUSINESS DEVELOPMENT—Christopher Moccia, Matrix Medical Communications, West Chester, Pennsylvania PARTNER—Patrick D. Scullin, Matrix Medical Communications, West Chester, Pennsylvania Innovations in Clinical Neuroscience, ISSN 2158-8333 (Print) and ISSN 2158-8341(Online), is published electronically 6 times yearly by Matrix Medical Communications via To receive an e-mail when a new issue is available and/or to access full content online, please visit and complete the online registration form. Registration and access are free to qualified professionals. Innovations in Clinical Neuroscience is not intended for patients or consumers. Indexing—Innovations in Clinical Neuroscience is indexed with PubMed Central, PsycINFO, CINAHL ® Plus Full Text, Scopus, and Embase. Editorial queries and submissions—Innovations in Clinical Neuroscience will consider suitable manuscripts for publication. All submissions must undergo peer review. Visit for author guidelines and access to online submission platform. Please direct all editorial queries to Elizabeth Klumpp at (484) 266-0702 or Advertising queries—Innovations in Clinical Neuroscience accepts advertisements on the website (, within the flipbook, and within the email newsletters. Please direct all advertising queries to Robert Dougherty at (484) 266-0702 or Copyright © 2017 Matrix Medical Communications. All rights reserved. Opinions expressed by authors, contributors, and advertisers are their own and not necessarily those of Matrix Medical Communications, the editorial staff, or any member of the editorial advisory board. Matrix Medical Communications is not responsible for accuracy of dosages given in the articles printed herein. The appearance of advertisements in this journal is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality, or safety. Matrix Medical Communications disclaims responsibility for any injury to persons or property resulting from any ideas or products referred to in the articles or advertisements. Matrix Medical Communications, LLC, 1595 Paoli Pike, Suite 201, West Chester, PA 19355, Phone 866.325.9975, Phone 484.266.0702, Fax 484.266.0726 V O L . 1 4 , N O . 1 – 2 S U P P L E M E N T , J A N U A R Y – F E B R U A R Y 2 0 1 6 October 27–30, 2016 Boca Raton, Florida Dear Colleagues: Welcome to the annual CNS Summit Abstracts of Poster Presentations supplement to Innovations in Clinical Neuroscience. We are pleased to provide you with this reference guide to some of the innovative research that was presented during CNS Summit 2016, which was held October 27 to 30 in Boca Raton, Florida. The supplement is also available online by visiting This supplement is just a small representation of what has become the premier event each year in drug development. Over 500 leaders in the field attended CNS Summit 2016 to experience more than 50 illuminating talks and witness the unveiling of 26 new innovations, such as Zephyr Illuminate ™ , a next generation enterprise solution that integrates global health data from thousands of disconnected sources, and AiCure's artificial intelligence platform, a mobile technology that provides visual confirmation of drug ingestion by patients . And during the meeting, #CNSSummit was the second leading hashtag trending on Twitter—a testament to the excitement and enthusiasm the Summit generates among its participants. This year, CNS Summit 2017: Collaborating for Novel Solutions will expand beyond just neuroscience and will explore drug development across multiple medical markets. The CNS Summit is committed to collaboration among all stakeholders involved in drug development, and we believe collaboration and data sharing with those involved in research across a wide variety of disease states will create more opportunity for developing better, safer, and more accessible drugs universally and within all areas of healthcare. In this abstract supplement, we've organized and cross-referenced CNS Summit 2016 poster abstracts into the following groups for your convenience and easy reference: • Artificial Intelligence/Machine Learning • Biomarkers and Imaging • Computer-based Tools • Digital Medicine • Investigative Drug Compounds and Therapies • Mobile Technology • Patient Assessment and Adherence • Placebo Response • Rater Assessment and Training • Trial Methodology/Study Protocol You will also find an alphabetical index by author and poster title on pages 22 and 23 of this publication. We hope you find the CNS Summit 2016 poster abstract supplement informative and that it provides a useful snapshot of the research that is presented during the CNS Summit each year. Make sure to mark your calendars for CNS Summit 2017, which will be November 16 to 19 at the Boca Raton Resort in Florida. We'll have more enlightening talks and innovative reveals than ever before, and you won't want to miss the opportunity to learn about the latest technology and innovations in drug development and network with leaders in the field. Use promotion code ICNS2017 when registering for the CNS Summit, and you will receive $100 off your registration fee. Visit for more information. Sincerely Amir Kalali, MD Editor, Innovations in Clinical Neuroscience Abstracts of Poster Presentations 2016

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