Innovations In Clinical Neuroscience

Pain Management August 2016

A peer-reviewed, evidence-based journal for clinicians in the field of neuroscience

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Hot Topics in Pain Management [August 2016] 12 average at 4.83 mmol/L. 204 male patients have maximum, minimal and average cholesterol level at 6.84, 1.31, and 4.41 mmol/L respectively. In addition, because of these different distributions of female and male patients on cholesterol level, they were analyzed separately. Serum total cholesterol levels correlate with BMIs. Before starting the actual analysis, correlations were determined between serum total cholesterol levels and ages, between BMIs and ages, and between serum total cholesterol levels and BMIs. By using Pearson test, no significant correlation was identified between serum total cholesterol levels and ages. P values were 0.8727 for female and 0.2647 for male (Fig. 1c-d). In addition, BMIs did not correlate significantly with ages (Fig. 1e-f). In female patients, Pearson's rank correlation coefficient was 0.1507 (P = 0.1878, Gaussian approximation, n = 78). In male patients, Pearson's rank correlation coefficient was −0.0389 (P = 0.5810, Gaussian approximation, n = 204). However, consistent with previous report [6], there was significant correlation between BMIs and serum total cholesterol levels, suggesting patients with higher BMIs may have higher cholesterol levels (Fig. 1g-h). In female patients, Pearson's rank correlation coefficient was 0.5089 (P < 0.0001, Gaussian approximation, n = 78). In male patients, Pearson's rank correlation coefficient was −0.3093 (P < 0.0001, Gaussian approximation, n = 204). Low cholesterol patients have larger percentage to not respond to initial doses. 78 female and 204 male patients were further divided into high cholesterol, medium cholesterol and low cholesterol groups basing on their serum total cholesterol levels. Each group included about one-third patients and the resulted medium cholesterol group had similar average cholesterol levels to those of original groups. In female patients, 28 patients (<4.35 mmol/L) were classified into low cholesterol group with an averaged cholesterol level at 3.73 mmol/L, 25 patients (>4.35 and <5.30 mmol/L) into medium group with an average at 4.82 mmol/L, while the other 25 patients (>5.30 mmol/L) into high group with an

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